Salbutamol Is A Medication That Opens Up The Medium And Large Airways In The Lungs. It Is Used To Treat Asthma, Exercise-induced Bronchospasm And Chronic Obstructive Pulmonary Disease (Copd). It May Also Be Used To Treat High Blood Potassium Levels. It Is Usually Used By Nebulizer, Pill, Inhaler, And Intravenous Solution. Albuterol/salbutamol Is Used To Treat Wheezing & Shortness Of Breath Caused By Breathing Problems (Such As Asthma, Chronic Obstructive Pulmonary Disease). It Belongs To Bronchodilators Group. In Vitro Studies And In Vivo Pharmacologic Studies Have Demonstrated That Albuterol Has A Preferential Effect On Beta2-adrenergic Receptors Compared To Isoproterenol. Activation Of Beta2-adrenergic Receptors On Airway Smooth Muscle Leads To The Activation Of Adenylcyclase And To An Increase In The Intracellular Concentration Of Cyclic-3',5'-adenosine Monophosphate (Cyclic Amp). Increase Of Cyclic Amp Leads To The Activation Of Protein Kinase A, Which Inhibits The Phosphorylation Of Myosin And Lowers Intracellular Ionic Calcium Concentrations, Resulting In Relaxation.
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